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- Early prophase: chromatin coils to form chromosomes, nuclear membrane disappears, and centrioles migrate to opposite poles of the cell.
- Middle prophase: spindle fibers, microtubules of protein, begin developing.
- Polar fibers extend across the cell from centriole to centriole.
- Kinetochore fibers extend from the centromeres of a chromosome to the centrioles.
- Late prophase: protein fibers called asters radiate from each centriole in animal cells.
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- Kinetochore fibers move the chromosomes to the equator of the cell.
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- The centromere of each pair of chromatids divides, the chromatids separate and are pushed to opposite poles of the cell by the combined efforts of the spindle fibers.
- This movement is done in one quick motion.
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- All spindle fibers disappear, chromatids unwind and stretch to form chromatin, and a nuclear membrane forms around each mass of chromatin.
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In any fast growing tissue, cells will be found in all phases of the cell cycle.
This is a picture of the very fast growing tissue of an onion root tip.
Notice the different size of the cells and the obvious mitosis phases.
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